Changes in skin texture, hydration or firmness can develop gradually. At Aventis, we begin by understanding your concerns and discussing whether a Salmon Sperm Facial could suit your skin.
The treatment uses purified DNA-derived ingredients from salmon to improve skin hydration, elasticity, and fine lines. Your practitioner will explain the product we use and the changes you may expect.
The regenerative skin treatment uses polynucleotides (PDRN) derived from purified salmon or trout DNA to support skin repair and rejuvenation. Polynucleotides are long chains of nucleotides that closely resemble human DNA, allowing them to work deep within the skin to stimulate regeneration.
Unlike filler treatments, Salmon Sperm works as a biostimulator, encouraging the skin to strengthen itself. When injected, the polynucleotides stimulate fibroblast activity, which helps boost collagen production, improve hydration, and support tissue repair.
As an active ingredient, PDRN also activates specific cellular receptors known as A2A, which accelerate processes that promote new blood vessel formation, reduce inflammation, and support the skin’s natural regenerative processes.
We may recommend the Salmon Sperm Facial for patients looking to improve their overall skin quality and address concerns such as:
All skin treatments begin with a consultation to assess your skin concerns and determine whether the Salmon Sperm Facial is the most appropriate treatment for you.
During the procedure, our aestheticians cleanse and prepare the skin before injecting polynucleotide via microneedling or microneedle injections. The full treatment typically takes between 30 and 60 minutes. Some mild redness is normal afterwards, but it usually settles quickly.
For more on caring for ageing skin, read our guide.
See our before-and-after gallery.
1. What is a Salmon Sperm Facial?
Also called a PDRN (Polydeoxyribonucleotide) facial, this regenerative skin treatment uses polynucleotides derived from purified salmon or trout DNA to support skin repair, improve hydration, and boost collagen production.
2. What skin concerns can a Salmon Sperm Facial help with?
The treatment helps with fine lines, early signs of ageing, dull or tired-looking skin, dehydration, uneven skin tone, loss of elasticity, and issues such as under-eye dark circles.
3. What can I expect during and after treatment?
The treatment takes 30 to 60 minutes. The skin is cleansed, and the polynucleotide is delivered by microneedle injections. Downtime is minimal, though mild redness may occur immediately afterwards and fade quickly. Results tend to develop gradually over the following weeks.
Last Medically Reviewed: 9th October 2026 by Dr Imogen Bexfield.
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