The Salmon Sperm Facial, also known as a PDRN facial, is one of the latest breakthroughs in skin rejuvenation. Often injected or microneedled to treat under-eye dark circles, facial sagging, and fine lines, it’s hailed by celebrities and patients worldwide for results that develop over 6-12 weeks.
The luxurious and revolutionary facial treatment harnesses the power of polynucleotides derived from salmon DNA to stimulate cellular regeneration and support the skin’s natural healing process, making it scientifically backed to help improve skin elasticity, reduce fine lines and boost hydration.

The regenerative skin treatment uses polynucleotides (PDRN) derived from purified salmon or trout DNA to support skin repair and rejuvenation. The polynucleotides are long chains of nucleotides, which closely resemble and mimic human DNA, allowing them to work effectively from deep within the skin to stimulate regeneration.
Unlike filler treatments, Salmon Sperm works as a biostimulator, encouraging the skin to strengthen itself. When injected, the polynucleotides stimulate fibroblast activity, which helps boost collagen production, improve hydration, and support tissue repair.
As an active ingredient, PDRN also activates specific cellular receptors known as A2A, which accelerate processes that promote new blood vessel formation, reduce inflammation, and support the skin’s natural regenerative processes.

The Salmon Sperm Facial is great for patients looking to improve their overall skin quality and address concerns such as:

All skin treatments begin with a consultation to assess your skin concerns and determine whether the Salmon Sperm Facial is the most appropriate treatment for you.
During the procedure, our aestheticians cleanse and prepare the skin before the polynucleotide is injected into the skin via microneedling or microneedle injections. The full treatment typically takes between 30 and 60 minutes. Some mild redness can be expected afterwards, but it usually settles quickly.

EXCELLENT
Based on 165 reviews
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RashanaTrustindex verifies that the original source of the review is Google.
One of my go-to aesthetics clinics in Cayman. Dr Imogen, Sena, and all the admin staff are amazing at what they do. I always feel welcome, and my results are always spot on. Highly recommend!Posted on Google![]()
Jennifer MoseleyTrustindex verifies that the original source of the review is Google.
I've been seeing Imogen for several years now and wouldn't go anywhere else. The whole team at Aventis is always so warm and welcoming, and the clinic itself is beautiful. Over the years I've had Botox, Aqualyx, moved entirely to medical-grade skincare, and laser treatments. The difference in my skin has been incredible. Growing up in Cayman and spending years working on the water, I wasn't always the best at looking after my skin, so having Imogen's guidance has been invaluable. My goal has never been to stop ageing, but to age gracefully, and I'm genuinely so happy with the results so far. Highly recommend Imogen and the Aventis team.Posted on Google![]()
Courtney JasonTrustindex verifies that the original source of the review is Google.
Imogen and her team at Aventis are truly second to none. They are the only people I trust with my Botox, fillers, and facial treatments. They have mastered the art of enhancing natural beauty while always making you feel comfortable and cared for. The office is immaculate yet warm and welcoming—it truly feels like home. I simply love them all and cannot recommend them highly enough!Posted on Google![]()
Timothy EvansTrustindex verifies that the original source of the review is Google.
My Botox and veneer appointment was amazing, so quick, pain free, and the results are more than I could expect. Dr Jonathan Lavington was incredibly professional and my cosmetic dentistry was better than I could expect. Dr Imogen Bexfield work is impeccable and I would highly recommend.Posted on Google![]()
Helios CaymanTrustindex verifies that the original source of the review is Google.
Dr. Johnny is a highly skilled and meticulous professional. He performed my first root canal in under 45 minutes, ensuring I was completely comfortable and pain-free throughout the entire process. Exceptional care from start to finish—I highly recommend this dental practice for any procedure.Posted on Google![]()
Hallie GiuzioTrustindex verifies that the original source of the review is Google.
Great experience at Aventis from start to finish. The team was welcoming, professional and made the whole process feel easy and comfortable. Dr. Childers and Victoria were both excellent, thorough, knowledgeable and incredibly attentive throughout. Really impressed with the level of care and service. Highly recommend AventisPosted on Google![]()
T. Kitti ConollyTrustindex verifies that the original source of the review is Google.
Every single person is friendly and helpful. Really great at dealing with kids and anyone who has a fear of the dentist. I can’t recommend them highly enough.Posted on Google![]()
Amanda Wong BoddenTrustindex verifies that the original source of the review is Google.
I had a very positive experience with Aventis. Their offices are pristine, modern and incredibly calming, which immediately helps to make a dental visit feel less daunting. Our child required a little extra care and patience as he is non-speaking and has significant sensory sensitivities, so finding a dental team that could understand and accommodate his needs was particularly important to us. Dr. Childers and Victoria were wonderful — patient, understanding, gentle and reassuring throughout the entire process. They took the time to work with him at his pace, communicate clearly with us and make what could otherwise have been a very stressful experience feel much more manageable. We genuinely felt that our child was in capable and caring hands. I would highly recommend Dr. Childers and the team at Aventis, particularly to families whose children may need a little more patience, understanding or individualized care during a dental visit.
See our before-and-after gallery.
1. What is a Salmon Sperm Facial?
Called a PDRN (Polydeoxyribonucleotide) facial, it is a regenerative skin treatment that uses polynucleotides derived from purified salmon or trout DNA to support skin repair, improve hydration, and boost collagen production.
2. What skin concerns can a Salmon Sperm Facial help with?
Treatment helps with fine lines, early signs of ageing, dull or tired-looking skin, dehydration, uneven skin tone, loss of elasticity, and problems such as under-eye dark circles.
3. During and after the treatment?
The treatment takes 30 to 60 minutes. The skin is cleansed, and the polynucleotide is delivered by microneedle injections. Downtime is minimal, though mild redness may occur immediately afterwards and fade quickly. Results tend to develop gradually over the following weeks.
Last Medically Reviewed: 8th September 2026 by Dr Imogen Bexfield.https://www.aventis.ky/treatment/pdo-thread-lifting/
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
Trustindex verifies that the original source of the review is Google.
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